MicroRNA-575 regulates development of gastric cancer by targeting PTEN
نویسندگان
چکیده
منابع مشابه
microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
Gastric cancer is one of the most common carcinomas in China. microRNAs, a type of non-coding RNA, are important specific regulators and are involved in numerous bioprocesses of an organism. microRNA-21 (miR-21) has been identified as the most suitable choice for further investigation because it is overexpressed in nearly all solid tumors; furthermore, it has been demonstrated that miR-21 is in...
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Objective: To investigate the biological significance of abundant miR-23a expression in gastric cancer (GC) and its correlation with PTEN in the pathogenesis of GC migration and invasion. Methods: The human gastric cancer cell lines SGC-7901, AGS, the immortalized cell line GES-1 derived from normal gastric mucosa. Cell transfection and selection of stable cell lines and the gene and protein le...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2019.108716